In humans, fungal infections can range from the common, such as tinea pedis or athletes foot, to the rare and exotic, such as sporotrichosis or agranulomatous disease. Two general types of fungal infections exist; topical (superficial) infections, affecting the skin and the mucous membranes, and systematic infections, affecting the areas such as the lungs, central nervous system, and the blood. Treating either type of infection requires a topical, oral, or parenteral agent chosen according to the site and severity of the infection.